Depression Profile – Males
£164.00 + £20 phlebotomy fee per donation
A Targeted Blood Test for Men’s Mental Health
Depression in men often goes unrecognised or untreated, in part because symptoms can present differently—more as fatigue, low drive, irritability, or concentration problems than overt sadness. While life stressors and emotional factors play a role, there’s growing recognition that hormonal shifts, thyroid function, and nutrient deficiencies can significantly affect mental well-being.
The Depression Profile – Males is a specialised blood test that investigates these biological factors. Designed specifically for men, it evaluates a wide range of hormonal, thyroid, metabolic, and nutritional markers that are frequently linked to mood changes, low energy, and reduced libido.
What Does This Test Measure?
This in-depth profile includes:
Hormonal Health
Testosterone – Vital for mood, motivation, energy, and libido
Estradiol (E2) – Affects emotional balance and cognitive function
Progesterone (PRG) – Regulates nervous system and sleep cycles
Luteinizing Hormone (LH) & Follicle-Stimulating Hormone (FSH) – Influence testosterone production and fertility
Thyroid Function
Thyroid-Stimulating Hormone (TSH)
Free Thyroxine (FT4)
Low thyroid function (hypothyroidism) is a common contributor to fatigue, sluggishness, and depressive symptoms.
Nutrient Status
Vitamin B12 – Essential for brain health, mood regulation, and energy production
Metabolic & Inflammatory Markers
Glucose
Glycated Haemoglobin (HbA1c) – Long-term blood sugar balance
Cholesterol (Total & HDL)
Rheumatoid Factor Quantitative – Assesses systemic inflammation
Full Blood Count (FBC) + Differential – Checks for anaemia, infection, and immune changes
Understanding Depression in Men
Depression in men can sometimes be harder to detect. Symptoms often manifest as:
Persistent tiredness or burnout
Irritability and frustration
Difficulty focusing or making decisions
Loss of motivation or drive
Sleep disruptions or appetite changes
Low libido or sexual performance concerns
Hormonal changes—especially low testosterone—as well as thyroid imbalances or deficiencies in vitamin B12 can mimic or worsen these symptoms. This test helps identify whether a physiological imbalance may be playing a role, so you can address the root cause, not just the symptoms.
Who Should Consider This Test?
This test is ideal for men who are:
Experiencing ongoing low mood, energy loss, or stress
Struggling with reduced focus, motivation, or libido
Suspecting hormonal changes, particularly over age 40
Seeking to explore biological contributors to their emotional state
Looking to support their mental health with targeted, evidence-based insights
Why Choose the Depression Profile – Males?
Fast lab results – within 4 hours of sample analysis
Comprehensive coverage of mood-related biomarkers
Supports early detection of low testosterone, thyroid dysfunction, or nutrient deficiency
Helps personalise a treatment or support strategy
Ideal complement to therapy or lifestyle changes
How the Test Works
Sample Type: Blood test (finger prick or venous draw)
Fasting: Required for 8–10 hours for accurate glucose and lipid readings
Turnaround Time: Results available in approx. 4 hours once the lab receives your sample
Phlebotomy Option: £20 fee for professional blood draw, if preferred
You’ll receive a clear digital report with reference ranges, interpretation, and guidance for follow-up steps.
Support Your Mental Health with Real Data
Mental health isn’t just emotional—it’s physical too. The Depression Profile – Males helps shine a light on the often-ignored biological factors that can undermine mood, energy, and mental clarity. Whether you’re navigating midlife changes, recovering from burnout, or simply looking for answers, this test offers clarity and a foundation for informed, proactive care.
